27x41" one-sheet poster for original 1939 release of Karloff mad scientist film, one of four he made for Columbia. Poster features great image of a menacing-looking Karloff looming over an unconscious bandaged patient as a woman screams behind him. Bubbling beakers and lab equipment are also seen. Classic foreboding imagery. Poster has been professionally linen-mounted and has a few scattered small touch-ups, which have restored the poster to its current bright and vibrant state, boasting rich, deep colors and displaying Exc.